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Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy
The term epigenetics is defined as heritable changes in gene expression that are not due to alterations of the DNA sequence. In the last years, it has become more and more evident that dysregulated epigenetic regulatory processes have a central role in cancer onset and progression. In contrast to DN...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877953/ https://www.ncbi.nlm.nih.gov/pubmed/27222667 http://dx.doi.org/10.1186/s13148-016-0223-4 |