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The MK2/HuR signaling pathway regulates TNF-α-induced ICAM-1 expression by promoting the stabilization of ICAM-1 mRNA

BACKGROUND: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are characterized by acute lung inflammation. Intercellular adhesion molecule-1 (ICAM-1) and interleukin-8 (IL-8) play an important role in the development of these diseases. Mitogen-activated protein kinase (MAPK) p3...

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Detalles Bibliográficos
Autores principales: Wu, Ting, Shi, Jia-Xin, Geng, Shen, Zhou, Wei, Shi, Yi, Su, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877999/
https://www.ncbi.nlm.nih.gov/pubmed/27215284
http://dx.doi.org/10.1186/s12890-016-0247-8

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