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Progesterone receptor blockade in human breast cancer cells decreases cell cycle progression through G2/M by repressing G2/M genes

BACKGROUND: The synthesis of specific, potent progesterone antagonists adds potential agents to the breast cancer prevention and treatment armamentarium. The identification of individuals who will benefit from these agents will be a critical factor for their clinical success. METHODS: We utilized te...

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Detalles Bibliográficos
Autores principales: Clare, Susan E., Gupta, Akash, Choi, MiRan, Ranjan, Manish, Lee, Oukseub, Wang, Jun, Ivancic, David Z., Kim, J. Julie, Khan, Seema A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878043/
https://www.ncbi.nlm.nih.gov/pubmed/27215412
http://dx.doi.org/10.1186/s12885-016-2355-5