miRNA-dependent target regulation: functional characterization of single-nucleotide polymorphisms identified in genome-wide association studies of Alzheimer’s disease

BACKGROUND: A growing body of evidence suggests that microRNAs (miRNAs) are involved in Alzheimer’s disease (AD) and that some disease-associated genetic variants are located within miRNA binding sites. In the present study, we sought to characterize functional polymorphisms in miRNA target sites wi...

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Detalles Bibliográficos
Autores principales: Delay, Charlotte, Grenier-Boley, Benjamin, Amouyel, Philippe, Dumont, Julie, Lambert, Jean-Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878064/
https://www.ncbi.nlm.nih.gov/pubmed/27215977
http://dx.doi.org/10.1186/s13195-016-0186-x

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