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Division of labor in the growth cone by DSCR1

Local protein synthesis directs growth cone turning of nascent axons, but mechanisms governing this process within compact, largely autonomous microenvironments remain poorly understood. In this issue, Wang et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201510107) demonstrate that the cal...

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Detalles Bibliográficos
Autores principales: Catlett, Timothy S., Gomez, Timothy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878096/
https://www.ncbi.nlm.nih.gov/pubmed/27216257
http://dx.doi.org/10.1083/jcb.201605012
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author Catlett, Timothy S.
Gomez, Timothy M.
author_facet Catlett, Timothy S.
Gomez, Timothy M.
author_sort Catlett, Timothy S.
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description Local protein synthesis directs growth cone turning of nascent axons, but mechanisms governing this process within compact, largely autonomous microenvironments remain poorly understood. In this issue, Wang et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201510107) demonstrate that the calcineurin regulator Down syndrome critical region 1 protein modulates both basal neurite outgrowth and growth cone turning.
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spelling pubmed-48780962016-11-23 Division of labor in the growth cone by DSCR1 Catlett, Timothy S. Gomez, Timothy M. J Cell Biol Commentary Local protein synthesis directs growth cone turning of nascent axons, but mechanisms governing this process within compact, largely autonomous microenvironments remain poorly understood. In this issue, Wang et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201510107) demonstrate that the calcineurin regulator Down syndrome critical region 1 protein modulates both basal neurite outgrowth and growth cone turning. The Rockefeller University Press 2016-05-23 /pmc/articles/PMC4878096/ /pubmed/27216257 http://dx.doi.org/10.1083/jcb.201605012 Text en © 2016 Catlett and Gomez This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Commentary
Catlett, Timothy S.
Gomez, Timothy M.
Division of labor in the growth cone by DSCR1
title Division of labor in the growth cone by DSCR1
title_full Division of labor in the growth cone by DSCR1
title_fullStr Division of labor in the growth cone by DSCR1
title_full_unstemmed Division of labor in the growth cone by DSCR1
title_short Division of labor in the growth cone by DSCR1
title_sort division of labor in the growth cone by dscr1
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878096/
https://www.ncbi.nlm.nih.gov/pubmed/27216257
http://dx.doi.org/10.1083/jcb.201605012
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