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Division of labor in the growth cone by DSCR1
Local protein synthesis directs growth cone turning of nascent axons, but mechanisms governing this process within compact, largely autonomous microenvironments remain poorly understood. In this issue, Wang et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201510107) demonstrate that the cal...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878096/ https://www.ncbi.nlm.nih.gov/pubmed/27216257 http://dx.doi.org/10.1083/jcb.201605012 |
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author | Catlett, Timothy S. Gomez, Timothy M. |
author_facet | Catlett, Timothy S. Gomez, Timothy M. |
author_sort | Catlett, Timothy S. |
collection | PubMed |
description | Local protein synthesis directs growth cone turning of nascent axons, but mechanisms governing this process within compact, largely autonomous microenvironments remain poorly understood. In this issue, Wang et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201510107) demonstrate that the calcineurin regulator Down syndrome critical region 1 protein modulates both basal neurite outgrowth and growth cone turning. |
format | Online Article Text |
id | pubmed-4878096 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-48780962016-11-23 Division of labor in the growth cone by DSCR1 Catlett, Timothy S. Gomez, Timothy M. J Cell Biol Commentary Local protein synthesis directs growth cone turning of nascent axons, but mechanisms governing this process within compact, largely autonomous microenvironments remain poorly understood. In this issue, Wang et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201510107) demonstrate that the calcineurin regulator Down syndrome critical region 1 protein modulates both basal neurite outgrowth and growth cone turning. The Rockefeller University Press 2016-05-23 /pmc/articles/PMC4878096/ /pubmed/27216257 http://dx.doi.org/10.1083/jcb.201605012 Text en © 2016 Catlett and Gomez This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/). |
spellingShingle | Commentary Catlett, Timothy S. Gomez, Timothy M. Division of labor in the growth cone by DSCR1 |
title | Division of labor in the growth cone by DSCR1 |
title_full | Division of labor in the growth cone by DSCR1 |
title_fullStr | Division of labor in the growth cone by DSCR1 |
title_full_unstemmed | Division of labor in the growth cone by DSCR1 |
title_short | Division of labor in the growth cone by DSCR1 |
title_sort | division of labor in the growth cone by dscr1 |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878096/ https://www.ncbi.nlm.nih.gov/pubmed/27216257 http://dx.doi.org/10.1083/jcb.201605012 |
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