Hepatic and Extrahepatic Insulin Clearance Are Differentially Regulated: Results From a Novel Model-Based Analysis of Intravenous Glucose Tolerance Data

Insulin clearance is a highly variable and important factor that affects circulating insulin concentrations. We developed a novel model-based method to estimate both hepatic and extrahepatic insulin clearance using plasma insulin and C-peptide profiles obtained from the insulin-modified frequently s...

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Detalles Bibliográficos
Autores principales: Polidori, David C., Bergman, Richard N., Chung, Stephanie T., Sumner, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878413/
https://www.ncbi.nlm.nih.gov/pubmed/26993071
http://dx.doi.org/10.2337/db15-1373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878413/
https://www.ncbi.nlm.nih.gov/pubmed/26993071
http://dx.doi.org/10.2337/db15-1373

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