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Hepatic and Extrahepatic Insulin Clearance Are Differentially Regulated: Results From a Novel Model-Based Analysis of Intravenous Glucose Tolerance Data

Insulin clearance is a highly variable and important factor that affects circulating insulin concentrations. We developed a novel model-based method to estimate both hepatic and extrahepatic insulin clearance using plasma insulin and C-peptide profiles obtained from the insulin-modified frequently s...

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Detalles Bibliográficos
Autores principales:	Polidori, David C., Bergman, Richard N., Chung, Stephanie T., Sumner, Anne E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2016
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878413/ https://www.ncbi.nlm.nih.gov/pubmed/26993071 http://dx.doi.org/10.2337/db15-1373

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