Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology

The risk of type 2 diabetes (T2D) is increased by abnormalities in sleep quantity and quality, circadian alignment, and melatonin regulation. A common genetic variant in a receptor for the circadian-regulated hormone melatonin (MTNR1B) is associated with increased fasting blood glucose and risk of T...

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Detalles Bibliográficos
Autores principales: Lane, Jacqueline M., Chang, Anne-Marie, Bjonnes, Andrew C., Aeschbach, Daniel, Anderson, Clare, Cade, Brian E., Cain, Sean W., Czeisler, Charles A., Gharib, Sina A., Gooley, Joshua J., Gottlieb, Daniel J., Grant, Struan F.A., Klerman, Elizabeth B., Lauderdale, Diane S., Lockley, Steven W., Munch, Miriam, Patel, Sanjay, Punjabi, Naresh M., Rajaratnam, Shanthakumar M.W., Rueger, Melanie, St. Hilaire, Melissa A., Santhi, Nayantara, Scheuermaier, Karin, Van Reen, Eliza, Zee, Phyllis C., Shea, Steven A., Duffy, Jeanne F., Buxton, Orfeu M., Redline, Susan, Scheer, Frank A.J.L., Saxena, Richa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878414/
https://www.ncbi.nlm.nih.gov/pubmed/26868293
http://dx.doi.org/10.2337/db15-0999

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