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Insulin Regulates Hepatic Triglyceride Secretion and Lipid Content via Signaling in the Brain
Hepatic steatosis is common in obesity and insulin resistance and results from a net retention of lipids in the liver. A key mechanism to prevent steatosis is to increase secretion of triglycerides (TG) packaged as VLDLs. Insulin controls nutrient partitioning via signaling through its cognate recep...
Autores principales: | Scherer, Thomas, Lindtner, Claudia, O’Hare, James, Hackl, Martina, Zielinski, Elizabeth, Freudenthaler, Angelika, Baumgartner-Parzer, Sabina, Tödter, Klaus, Heeren, Joerg, Krššák, Martin, Scheja, Ludger, Fürnsinn, Clemens, Buettner, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878422/ https://www.ncbi.nlm.nih.gov/pubmed/26861781 http://dx.doi.org/10.2337/db15-1552 |
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