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Synergistic Inhibitory Effects of Hypoxia and Iron Deficiency on Hepatic Glucose Response in Mouse Liver
Hypoxia and iron both regulate metabolism through multiple mechanisms, including hypoxia-inducible transcription factors. The hypoxic effects on glucose disposal and glycolysis are well established, but less is known about the effects of hypoxia and iron deficiency on hepatic gluconeogenesis. We the...
Autores principales: | Nam, Hyeyoung, Jones, Deborah, Cooksey, Robert C., Gao, Yan, Sink, Sandy, Cox, James, McClain, Donald A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878425/ https://www.ncbi.nlm.nih.gov/pubmed/26993063 http://dx.doi.org/10.2337/db15-0580 |
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