Ablation of the mitochondrial complex IV assembly protein Surf1 leads to increased expression of the UPR(MT) and increased resistance to oxidative stress in primary cultures of fibroblasts

Mice deficient in the electron transport chain (ETC) complex IV assembly protein SURF1 have reduced assembly and activity of cytochrome c oxidase that is associated with an upregulation of components of the mitochondrial unfolded protein response (UPR(MT)) and increased mitochondrial number. We hypo...

Descripción completa

Detalles Bibliográficos
Autores principales: Pharaoh, Gavin, Pulliam, Daniel, Hill, Shauna, Sataranatarajan, Kavithalakshmi, Van Remmen, Holly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878459/
https://www.ncbi.nlm.nih.gov/pubmed/27208630
http://dx.doi.org/10.1016/j.redox.2016.05.001

Ejemplares similares

Ejemplares similares