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DNase I aggravates islet β-cell apoptosis in type 2 diabetes

Deoxyribonuclease I (DNase I) is an endonuclease responsible for the destruction of chromatin during apoptosis. However, its role in diabetes remains unclear. The aim of the current study was to investigate the role of DNase I combined with high glucose levels in β-cell apoptosis. Human samples were...

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Detalles Bibliográficos
Autores principales: ZHU, BIN, ZHANG, LEI, ZHANG, YUE-YING, WANG, LEI, LI, XIN-GANG, LIU, TENG, FU, YU-KE, ZHENG, YAN-FEI, LI, PING, ZHAO, ZHI-GANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878546/
https://www.ncbi.nlm.nih.gov/pubmed/27082840
http://dx.doi.org/10.3892/mmr.2016.5102

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