Cargando…
DNase I aggravates islet β-cell apoptosis in type 2 diabetes
Deoxyribonuclease I (DNase I) is an endonuclease responsible for the destruction of chromatin during apoptosis. However, its role in diabetes remains unclear. The aim of the current study was to investigate the role of DNase I combined with high glucose levels in β-cell apoptosis. Human samples were...
Autores principales: | ZHU, BIN, ZHANG, LEI, ZHANG, YUE-YING, WANG, LEI, LI, XIN-GANG, LIU, TENG, FU, YU-KE, ZHENG, YAN-FEI, LI, PING, ZHAO, ZHI-GANG |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878546/ https://www.ncbi.nlm.nih.gov/pubmed/27082840 http://dx.doi.org/10.3892/mmr.2016.5102 |
Ejemplares similares
-
Deep learning for DNase I hypersensitive sites identification
por: Lyu, Chuqiao, et al.
Publicado: (2018) -
Lipid accelerating the fibril of islet amyloid polypeptide aggravated the pancreatic islet injury in vitro and in vivo
por: Mo, Xiao-Dan, et al.
Publicado: (2018) -
TERT and Akt Are Involved in the Par-4-Dependent Apoptosis of Islet β Cells in Type 2 Diabetes
por: Liu, Chen, et al.
Publicado: (2018) -
TNFα Amplifies DNaseI Expression in Renal Tubular Cells while IL-1β Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive Form
por: Thiyagarajan, Dhivya, et al.
Publicado: (2015) -
Genome-wide mapping of DNase I hypersensitive sites in pineapple leaves
por: Ouyang, Kai, et al.
Publicado: (2023)