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Cytoplasmic long noncoding RNAs are frequently bound to and degraded at ribosomes in human cells

Recent footprinting studies have made the surprising observation that long noncoding RNAs (lncRNAs) physically interact with ribosomes. However, these findings remain controversial, and the overall proportion of cytoplasmic lncRNAs involved is unknown. Here we make a global, absolute estimate of the...

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Detalles Bibliográficos
Autores principales: Carlevaro-Fita, Joana, Rahim, Anisa, Guigó, Roderic, Vardy, Leah A., Johnson, Rory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878613/
https://www.ncbi.nlm.nih.gov/pubmed/27090285
http://dx.doi.org/10.1261/rna.053561.115