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Palmitoylethanolamide Modulates Inflammation-Associated Vascular Endothelial Growth Factor (VEGF) Signaling via the Akt/mTOR Pathway in a Selective Peroxisome Proliferator-Activated Receptor Alpha (PPAR-α)-Dependent Manner
BACKGROUND AND AIM: Angiogenesis is emerging as a pivotal process in chronic inflammatory pathologies, promoting immune infiltration and prompting carcinogenesis. Ulcerative Colitis (UC) and Crohn’s Disease (CD) represent paradigmatic examples of intestinal chronic inflammatory conditions in which t...
Autores principales: | Sarnelli, Giovanni, D’Alessandro, Alessandra, Iuvone, Teresa, Capoccia, Elena, Gigli, Stefano, Pesce, Marcella, Seguella, Luisa, Nobile, Nicola, Aprea, Giovanni, Maione, Francesco, de Palma, Giovanni Domenico, Cuomo, Rosario, Steardo, Luca, Esposito, Giuseppe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878779/ https://www.ncbi.nlm.nih.gov/pubmed/27219328 http://dx.doi.org/10.1371/journal.pone.0156198 |
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