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The case for a Diels-Alderase-free, bis-pericyclic, [4+2] dimerization in the biosynthesis of (±)-paracaseolide A

The natural product paracaseolide A is a tetracyclic dilactone containing six adjacent stereocenters. It has an unprecedented skeleton and occupies unique structural space among the >200,000 characterized secondary metabolites. Six different research groups have reported a chemical synthesis of t...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Hoye, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878989/
https://www.ncbi.nlm.nih.gov/pubmed/26201740
http://dx.doi.org/10.1038/nchem.2281