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Biodegradable scaffold with built-in vasculature for organ-on-a-chip engineering and direct surgical anastomosis

We report the fabrication of a scaffold (hereafter referred to as AngioChip) that supports the assembly of parenchymal cells on a mechanically tunable matrix surrounding a perfusable, branched, three-dimensional microchannel network coated with endothelial cells. The design of AngioChip decouples th...

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Detalles Bibliográficos
Autores principales: Zhang, Boyang, Montgomery, Miles, Chamberlain, M. Dean, Ogawa, Shinichiro, Korolj, Anastasia, Pahnke, Aric, Wells, Laura A., Massé, Stéphane, Kim, Jihye, Reis, Lewis, Momen, Abdulah, Nunes, Sara S., Wheeler, Aaron, Nanthakumar, Kumaraswamy, Keller, Gordon, Sefton, Michael V., Radisic, Milica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879054/
https://www.ncbi.nlm.nih.gov/pubmed/26950595
http://dx.doi.org/10.1038/nmat4570