Two-pore Channels Enter the Atomic Era: Structure of Plant TPC Revealed

Two-pore channels (TPCs) are intracellular Ca(2+)-permeable ion channels that are expressed on acidic Ca(2+) stores. They are co-regulated by voltage and Ca(2+) in plant vacuoles and by the second messenger NAADP in animal endo-lysosomes. Two new studies of plant TPC structures reveal essential feat...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Sandip, Penny, Christopher J., Rahman, Taufiq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Trends Journals 2016
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879148/
https://www.ncbi.nlm.nih.gov/pubmed/27156118
http://dx.doi.org/10.1016/j.tibs.2016.04.007
_version_ 1782433642454188032
author Patel, Sandip
Penny, Christopher J.
Rahman, Taufiq
author_facet Patel, Sandip
Penny, Christopher J.
Rahman, Taufiq
author_sort Patel, Sandip
collection PubMed
description Two-pore channels (TPCs) are intracellular Ca(2+)-permeable ion channels that are expressed on acidic Ca(2+) stores. They are co-regulated by voltage and Ca(2+) in plant vacuoles and by the second messenger NAADP in animal endo-lysosomes. Two new studies of plant TPC structures reveal essential features of their architecture and provide mechanistic insight into their workings.
format Online
Article
Text
id pubmed-4879148
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Elsevier Trends Journals
record_format MEDLINE/PubMed
spelling pubmed-48791482016-06-02 Two-pore Channels Enter the Atomic Era: Structure of Plant TPC Revealed Patel, Sandip Penny, Christopher J. Rahman, Taufiq Trends Biochem Sci Spotlight Two-pore channels (TPCs) are intracellular Ca(2+)-permeable ion channels that are expressed on acidic Ca(2+) stores. They are co-regulated by voltage and Ca(2+) in plant vacuoles and by the second messenger NAADP in animal endo-lysosomes. Two new studies of plant TPC structures reveal essential features of their architecture and provide mechanistic insight into their workings. Elsevier Trends Journals 2016-06 /pmc/articles/PMC4879148/ /pubmed/27156118 http://dx.doi.org/10.1016/j.tibs.2016.04.007 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Spotlight
Patel, Sandip
Penny, Christopher J.
Rahman, Taufiq
Two-pore Channels Enter the Atomic Era: Structure of Plant TPC Revealed
title Two-pore Channels Enter the Atomic Era: Structure of Plant TPC Revealed
title_full Two-pore Channels Enter the Atomic Era: Structure of Plant TPC Revealed
title_fullStr Two-pore Channels Enter the Atomic Era: Structure of Plant TPC Revealed
title_full_unstemmed Two-pore Channels Enter the Atomic Era: Structure of Plant TPC Revealed
title_short Two-pore Channels Enter the Atomic Era: Structure of Plant TPC Revealed
title_sort two-pore channels enter the atomic era: structure of plant tpc revealed
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879148/
https://www.ncbi.nlm.nih.gov/pubmed/27156118
http://dx.doi.org/10.1016/j.tibs.2016.04.007
work_keys_str_mv AT patelsandip twoporechannelsentertheatomicerastructureofplanttpcrevealed
AT pennychristopherj twoporechannelsentertheatomicerastructureofplanttpcrevealed
AT rahmantaufiq twoporechannelsentertheatomicerastructureofplanttpcrevealed

Ejemplares similares