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Molecular Subtypes and Personalized Therapy in Metastatic Colorectal Cancer

Development of colorectal cancer occurs via a number of key pathways, with the clinicopathological features of specific subgroups being driven by underlying molecular changes. Mutations in key genes within the network of signalling pathways have been identified; however, therapeutic strategies to ta...

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Detalles Bibliográficos
Autores principales: Graham, Donna M., Coyle, Vicky M., Kennedy, Richard D., Wilson, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879165/
https://www.ncbi.nlm.nih.gov/pubmed/27340376
http://dx.doi.org/10.1007/s11888-016-0312-y