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Inflammasome signaling affects anxiety- and depressive-like behavior and gut microbiome composition
The inflammasome is hypothesized to be a key mediator of the response to physiological and psychological stressors, and its dysregulation may be implicated in major depressive disorder. Inflammasome activation causes the maturation of caspase-1 and activation of interleukin (IL)-1β and IL-18, two pr...
Autores principales: | Wong, M-L, Inserra, A, Lewis, M D, Mastronardi, C A, Leong, L, Choo, J, Kentish, S, Xie, P, Morrison, M, Wesselingh, S L, Rogers, G B, Licinio, J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879188/ https://www.ncbi.nlm.nih.gov/pubmed/27090302 http://dx.doi.org/10.1038/mp.2016.46 |
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