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CXXC finger protein 1 is critical for T-cell intrathymic development through regulating H3K4 trimethylation

T-cell development in the thymus is largely controlled by an epigenetic program, involving in both DNA methylation and histone modifications. Previous studies have identified Cxxc1 as a regulator of both cytosine methylation and histone 3 lysine 4 trimethylation (H3K4me3). However, it is unknown whe...

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Detalles Bibliográficos
Autores principales: Cao, Wenqiang, Guo, Jing, Wen, Xiaofeng, Miao, Li, Lin, Feng, Xu, Guanxin, Ma, Ruoyu, Yin, Shengxia, Hui, Zhaoyuan, Chen, Tingting, Guo, Shixin, Chen, Wei, Huang, Yingying, Liu, Yizhi, Wang, Jianli, Wei, Lai, Wang, Lie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879243/
https://www.ncbi.nlm.nih.gov/pubmed/27210293
http://dx.doi.org/10.1038/ncomms11687