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Leucocyte subset-specific type 1 interferon signatures in SLE and other immune-mediated diseases
OBJECTIVES: Type 1 interferons (IFN-1) are implicated in the pathogenesis of systemic lupus erythematosus (SLE), but most studies have only reported the effect of IFN-1 on mixed cell populations. We aimed to define modules of IFN-1-associated genes in purified leucocyte populations and use these as...
Autores principales: | Flint, Shaun M, Jovanovic, Vojislav, Teo, Boon Wee, Mak, Anselm, Thumboo, Julian, McKinney, Eoin F, Lee, James C, MacAry, Paul, Kemeny, David M, Jayne, David RW, Fong, Kok Yong, Lyons, Paul A, Smith, Kenneth GC |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879345/ https://www.ncbi.nlm.nih.gov/pubmed/27252891 http://dx.doi.org/10.1136/rmdopen-2015-000183 |
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