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Neuroprotective effects of the immunomodulatory drug FK506 in a model of HIV1-gp120 neurotoxicity
BACKGROUND: HIV-associated neurocognitive disorders (HAND) continue to be a common morbidity associated with chronic HIV infection. It has been shown that HIV proteins (e.g., gp120) released from infected microglial/macrophage cells can cause neuronal damage by triggering inflammation and oxidative...
Autores principales: | Fields, Jerel A., Overk, Cassia, Adame, Anthony, Florio, Jazmin, Mante, Michael, Pineda, Andrea, Desplats, Paula, Rockenstein, Edward, Achim, Cristian, Masliah, Eliezer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879748/ https://www.ncbi.nlm.nih.gov/pubmed/27220536 http://dx.doi.org/10.1186/s12974-016-0585-8 |
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