Exclusive expression of the Rab11 effector SH3TC2 in Schwann cells links integrin-α(6) and myelin maintenance to Charcot-Marie-Tooth disease type 4C

Charcot-Marie-Tooth disease type 4C (CMT4C) is one of the commonest autosomal recessive inherited peripheral neuropathies and is associated with mutations in the Rab11 effector, SH3TC2. Disruption of the SH3TC2–Rab11 interaction is the molecular abnormality underlying this disease. However, why SH3T...

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Detalles Bibliográficos
Autores principales: Vijay, Sauparnika, Chiu, Meagan, Dacks, Joel B., Roberts, Rhys C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879868/
https://www.ncbi.nlm.nih.gov/pubmed/27068304
http://dx.doi.org/10.1016/j.bbadis.2016.04.003

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