Delayed postoperative radiation therapy in local control of squamous cell carcinoma of the tongue and floor of the mouth

OBJECTIVE: To evaluate the effect of time between surgery and postoperative radiation therapy on local recurrence of squamous cell carcinoma of the tongue and floor of the mouth. METHODS: A total of 154 patients treated between 1996 and 2007 were selected considering local recurrence rate and time o...

Descripción completa

Detalles Bibliográficos
Autores principales: Amar, Ali, Chedid, Helma Maria, Curioni, Otávio Alberto, Dedivitis, Rogério Aparecido, Rapoport, Abrão, Cernea, Claudio Roberto, Brandão, Lenine Garcia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879915/
https://www.ncbi.nlm.nih.gov/pubmed/25628200
http://dx.doi.org/10.1590/S1679-45082014AO3006
Descripción
Sumario:OBJECTIVE: To evaluate the effect of time between surgery and postoperative radiation therapy on local recurrence of squamous cell carcinoma of the tongue and floor of the mouth. METHODS: A total of 154 patients treated between 1996 and 2007 were selected considering local recurrence rate and time of the adjuvant radiotherapy. RESULTS: Local recurrence was diagnosed in 54 (35%) patients. Radiation therapy reduced the rate of local recurrences, although with no statistical significance. The time between surgery and initiation of postoperative radiotherapy did not significantly influence the risk of local recurrence in patients referred to adjuvant treatment (p=0.49). CONCLUSION: In the presence of risk factors for local recurrence, a short delay in starting the adjuvant radiation therapy does not contraindicate its performance.

Ejemplares similares