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Shigella Antimicrobial Drug Resistance Mechanisms, 2004–2014

To determine antimicrobial drug resistance mechanisms of Shigella spp., we analyzed 344 isolates collected in Switzerland during 2004–2014. Overall, 78.5% of isolates were multidrug resistant; 10.5% were ciprofloxacin resistant; and 2% harbored mph(A), a plasmid-mediated gene that confers reduced su...

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Detalles Bibliográficos
Autores principales: Nüesch-Inderbinen, Magdalena, Heini, Nicole, Zurfluh, Katrin, Althaus, Denise, Hächler, Herbert, Stephan, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880098/
https://www.ncbi.nlm.nih.gov/pubmed/27191035
http://dx.doi.org/10.3201/eid2206.152088
Descripción
Sumario:To determine antimicrobial drug resistance mechanisms of Shigella spp., we analyzed 344 isolates collected in Switzerland during 2004–2014. Overall, 78.5% of isolates were multidrug resistant; 10.5% were ciprofloxacin resistant; and 2% harbored mph(A), a plasmid-mediated gene that confers reduced susceptibility to azithromycin, a last-resort antimicrobial agent for shigellosis.