Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus

We conducted a challenge/rechallenge trial in which 3 alpacas were infected with Middle East respiratory syndrome coronavirus. The alpacas shed virus at challenge but were refractory to further shedding at rechallenge on day 21. The trial indicates that alpacas may be suitable models for infection a...

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Detalles Bibliográficos
Autores principales: Crameri, Gary, Durr, Peter A., Klein, Reuben, Foord, Adam, Yu, Meng, Riddell, Sarah, Haining, Jessica, Johnson, Dayna, Hemida, Maged G., Barr, Jennifer, Peiris, Malik, Middleton, Deborah, Wang, Lin-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880109/
https://www.ncbi.nlm.nih.gov/pubmed/27070733
http://dx.doi.org/10.3201/eid2206.160007
Descripción
Sumario:We conducted a challenge/rechallenge trial in which 3 alpacas were infected with Middle East respiratory syndrome coronavirus. The alpacas shed virus at challenge but were refractory to further shedding at rechallenge on day 21. The trial indicates that alpacas may be suitable models for infection and shedding dynamics of this virus.

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