Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus

We conducted a challenge/rechallenge trial in which 3 alpacas were infected with Middle East respiratory syndrome coronavirus. The alpacas shed virus at challenge but were refractory to further shedding at rechallenge on day 21. The trial indicates that alpacas may be suitable models for infection a...

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Autores principales: Crameri, Gary, Durr, Peter A., Klein, Reuben, Foord, Adam, Yu, Meng, Riddell, Sarah, Haining, Jessica, Johnson, Dayna, Hemida, Maged G., Barr, Jennifer, Peiris, Malik, Middleton, Deborah, Wang, Lin-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880109/
https://www.ncbi.nlm.nih.gov/pubmed/27070733
http://dx.doi.org/10.3201/eid2206.160007
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author Crameri, Gary
Durr, Peter A.
Klein, Reuben
Foord, Adam
Yu, Meng
Riddell, Sarah
Haining, Jessica
Johnson, Dayna
Hemida, Maged G.
Barr, Jennifer
Peiris, Malik
Middleton, Deborah
Wang, Lin-Fa
author_facet Crameri, Gary
Durr, Peter A.
Klein, Reuben
Foord, Adam
Yu, Meng
Riddell, Sarah
Haining, Jessica
Johnson, Dayna
Hemida, Maged G.
Barr, Jennifer
Peiris, Malik
Middleton, Deborah
Wang, Lin-Fa
author_sort Crameri, Gary
collection PubMed
description We conducted a challenge/rechallenge trial in which 3 alpacas were infected with Middle East respiratory syndrome coronavirus. The alpacas shed virus at challenge but were refractory to further shedding at rechallenge on day 21. The trial indicates that alpacas may be suitable models for infection and shedding dynamics of this virus.
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spelling pubmed-48801092016-06-01 Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus Crameri, Gary Durr, Peter A. Klein, Reuben Foord, Adam Yu, Meng Riddell, Sarah Haining, Jessica Johnson, Dayna Hemida, Maged G. Barr, Jennifer Peiris, Malik Middleton, Deborah Wang, Lin-Fa Emerg Infect Dis Dispatch We conducted a challenge/rechallenge trial in which 3 alpacas were infected with Middle East respiratory syndrome coronavirus. The alpacas shed virus at challenge but were refractory to further shedding at rechallenge on day 21. The trial indicates that alpacas may be suitable models for infection and shedding dynamics of this virus. Centers for Disease Control and Prevention 2016-06 /pmc/articles/PMC4880109/ /pubmed/27070733 http://dx.doi.org/10.3201/eid2206.160007 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Crameri, Gary
Durr, Peter A.
Klein, Reuben
Foord, Adam
Yu, Meng
Riddell, Sarah
Haining, Jessica
Johnson, Dayna
Hemida, Maged G.
Barr, Jennifer
Peiris, Malik
Middleton, Deborah
Wang, Lin-Fa
Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus
title Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus
title_full Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus
title_fullStr Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus
title_full_unstemmed Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus
title_short Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus
title_sort experimental infection and response to rechallenge of alpacas with middle east respiratory syndrome coronavirus
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880109/
https://www.ncbi.nlm.nih.gov/pubmed/27070733
http://dx.doi.org/10.3201/eid2206.160007
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