Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior

Gene-environment interactions impact the development of neuropsychiatric disorders, but the relative contributions are unclear. Here, we identify gut microbiota as sufficient to induce depressive-like behaviors in genetically distinct mouse strains. Daily gavage of vehicle (dH2O) in nonobese diabeti...

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Detalles Bibliográficos
Autores principales: Gacias, Mar, Gaspari, Sevasti, Santos, Patricia-Mae G, Tamburini, Sabrina, Andrade, Monica, Zhang, Fan, Shen, Nan, Tolstikov, Vladimir, Kiebish, Michael A, Dupree, Jeffrey L, Zachariou, Venetia, Clemente, Jose C, Casaccia, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880443/
https://www.ncbi.nlm.nih.gov/pubmed/27097105
http://dx.doi.org/10.7554/eLife.13442

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