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Activation Mechanism of LRRK2 and Its Cellular Functions in Parkinson's Disease

Human LRRK2 (Leucine-Rich Repeat Kinase 2) has been associated with both familial and idiopathic Parkinson's disease (PD). Although several LRRK2 mediated pathways and interaction partners have been identified, the cellular functions of LRRK2 and LRRK2 mediated progression of PD are still only...

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Detalles Bibliográficos
Autores principales:	Rosenbusch, Katharina E., Kortholt, Arjan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880697/ https://www.ncbi.nlm.nih.gov/pubmed/27293958 http://dx.doi.org/10.1155/2016/7351985

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