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Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy
Bell's palsy (BP), an acute unilateral facial paralysis, is frequently treated with acupuncture in many countries. However, the mechanism of treatment is not clear so far. In order to explore the potential mechanism, 22 healthy volunteers and 17 BP patients with different clinical duration were...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880700/ https://www.ncbi.nlm.nih.gov/pubmed/27293461 http://dx.doi.org/10.1155/2016/5928758 |
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author | Bian, Yunpeng He, Xiaoxuan Hu, Sheng Li, Chuanfu Xu, Chunsheng Kan, Hongxing Xue, Qiuju Yang, Jun Qiu, Bensheng |
author_facet | Bian, Yunpeng He, Xiaoxuan Hu, Sheng Li, Chuanfu Xu, Chunsheng Kan, Hongxing Xue, Qiuju Yang, Jun Qiu, Bensheng |
author_sort | Bian, Yunpeng |
collection | PubMed |
description | Bell's palsy (BP), an acute unilateral facial paralysis, is frequently treated with acupuncture in many countries. However, the mechanism of treatment is not clear so far. In order to explore the potential mechanism, 22 healthy volunteers and 17 BP patients with different clinical duration were recruited. The resting-state functional magnetic resonance imaging scans were conducted before and after acupuncture at LI4 (Hegu), respectively. By comparing BP-induced functional connectivity (FC) changes with acupuncture-induced FC changes in the patients, the abnormal increased FC that could be reduced by acupuncture was selected. The FC strength of the selected FC at various stages was analyzed subsequently. Our results show that FC modulation of acupuncture is specific and consistent with the tendency of recovery. Therefore, we propose that FC modulation by acupuncture may be beneficial to recovery from the disease. |
format | Online Article Text |
id | pubmed-4880700 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-48807002016-06-12 Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy Bian, Yunpeng He, Xiaoxuan Hu, Sheng Li, Chuanfu Xu, Chunsheng Kan, Hongxing Xue, Qiuju Yang, Jun Qiu, Bensheng Evid Based Complement Alternat Med Research Article Bell's palsy (BP), an acute unilateral facial paralysis, is frequently treated with acupuncture in many countries. However, the mechanism of treatment is not clear so far. In order to explore the potential mechanism, 22 healthy volunteers and 17 BP patients with different clinical duration were recruited. The resting-state functional magnetic resonance imaging scans were conducted before and after acupuncture at LI4 (Hegu), respectively. By comparing BP-induced functional connectivity (FC) changes with acupuncture-induced FC changes in the patients, the abnormal increased FC that could be reduced by acupuncture was selected. The FC strength of the selected FC at various stages was analyzed subsequently. Our results show that FC modulation of acupuncture is specific and consistent with the tendency of recovery. Therefore, we propose that FC modulation by acupuncture may be beneficial to recovery from the disease. Hindawi Publishing Corporation 2016 2016-05-12 /pmc/articles/PMC4880700/ /pubmed/27293461 http://dx.doi.org/10.1155/2016/5928758 Text en Copyright © 2016 Yunpeng Bian et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Bian, Yunpeng He, Xiaoxuan Hu, Sheng Li, Chuanfu Xu, Chunsheng Kan, Hongxing Xue, Qiuju Yang, Jun Qiu, Bensheng Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy |
title | Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy |
title_full | Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy |
title_fullStr | Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy |
title_full_unstemmed | Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy |
title_short | Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy |
title_sort | functional connectivity modulation by acupuncture in patients with bell's palsy |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880700/ https://www.ncbi.nlm.nih.gov/pubmed/27293461 http://dx.doi.org/10.1155/2016/5928758 |
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