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Chromosome Compaction by Active Loop Extrusion
During cell division, chromosomes are compacted in length by more than a 100-fold. A wide range of experiments demonstrated that in their compacted state, mammalian chromosomes form arrays of closely stacked consecutive ∼100 kb loops. The mechanism underlying the active process of chromosome compact...
Autores principales: | Goloborodko, Anton, Marko, John F., Mirny, Leonid A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880799/ https://www.ncbi.nlm.nih.gov/pubmed/27224481 http://dx.doi.org/10.1016/j.bpj.2016.02.041 |
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