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Primary sex determination of placental mammals: a modelling study uncovers dynamical developmental constraints in the formation of Sertoli and granulosa cells

BACKGROUND: Primary sex determination in placental mammals is a very well studied developmental process. Here, we aim to investigate the currently established scenario and to assess its adequacy to fully recover the observed phenotypes, in the wild type and perturbed situations. Computational modell...

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Detalles Bibliográficos
Autores principales: Sánchez, Lucas, Chaouiya, Claudine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880855/
https://www.ncbi.nlm.nih.gov/pubmed/27229461
http://dx.doi.org/10.1186/s12918-016-0282-3