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Primary sex determination of placental mammals: a modelling study uncovers dynamical developmental constraints in the formation of Sertoli and granulosa cells
BACKGROUND: Primary sex determination in placental mammals is a very well studied developmental process. Here, we aim to investigate the currently established scenario and to assess its adequacy to fully recover the observed phenotypes, in the wild type and perturbed situations. Computational modell...
Autores principales: | Sánchez, Lucas, Chaouiya, Claudine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880855/ https://www.ncbi.nlm.nih.gov/pubmed/27229461 http://dx.doi.org/10.1186/s12918-016-0282-3 |
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