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Frizzled7: A Promising Achilles’ Heel for Targeting the Wnt Receptor Complex to Treat Cancer

Frizzled7 is arguably the most studied member of the Frizzled family, which are the cognate Wnt receptors. Frizzled7 is highly conserved through evolution, from Hydra through to humans, and is expressed in diverse organisms, tissues and human disease contexts. Frizzled receptors can homo- or hetero-...

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Detalles Bibliográficos
Autores principales: Phesse, Toby, Flanagan, Dustin, Vincan, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880867/
https://www.ncbi.nlm.nih.gov/pubmed/27196929
http://dx.doi.org/10.3390/cancers8050050