Cargando…

The MYC 3′ Wnt-Responsive Element Drives Oncogenic MYC Expression in Human Colorectal Cancer Cells

Mutations in components of the Wnt/β-catenin signaling pathway drive colorectal cancer (CRC) by deregulating expression of downstream target genes including the c-MYC proto-oncogene (MYC). The critical regulatory DNA enhancer elements that control oncogenic MYC expression in CRC have yet to be fully...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rennoll, Sherri A., Eshelman, Melanie A., Raup-Konsavage, Wesley M., Kawasawa, Yuka Imamura, Yochum, Gregory S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880869/ https://www.ncbi.nlm.nih.gov/pubmed/27223305 http://dx.doi.org/10.3390/cancers8050052

Ejemplares similares

Transcriptome Analyses Identify Deregulated MYC in Early Onset Colorectal Cancer
por: Marx, Olivia M., et al.
Publicado: (2022)

The Crohn’s disease associated SNP rs6651252 impacts MYC gene expression in human colonic epithelial cells
por: Matthews, Stephen M., et al.
Publicado: (2019)

Synthetic Cannabinoid Activity Against Colorectal Cancer Cells
por: Raup-Konsavage, Wesley M., et al.
Publicado: (2018)

Multiple Wnt/ß-Catenin Responsive Enhancers Align with the MYC Promoter through Long-Range Chromatin Loops
por: Yochum, Gregory S.
Publicado: (2011)

Special Issue: Therapeutic Potential for Cannabis and Cannabinoids
por: Raup-Konsavage, Wesley M.
Publicado: (2023)

Clinical significance of high c-MYC and low MYCBP2 expression and their association with Ikaros dysfunction in adult acute lymphoblastic leukemia
por: Ge, Zheng, et al.
Publicado: (2015)

Wnt signaling promotes oncogenic transformation by inhibiting c-Myc–induced apoptosis
por: You, Zongbing, et al.
Publicado: (2002)

Over-expression of the c-myc proto-oncogene in colorectal carcinoma.
por: Smith, D. R., et al.
Publicado: (1993)

Correction: Wnt signaling promotes oncogenic transformation by inhibiting c-Myc–induced apoptosis
por: You, Zongbing, et al.
Publicado: (2021)

Coamplification of the L‐myc and N‐myc Oncogenes in a Neuroblastoma Cell Line
por: Jinbo, Takeshi, et al.
Publicado: (1989)

Oncogenic MYC amplifies mitotic perturbations
por: Littler, Samantha, et al.
Publicado: (2019)

Tristetraprolin targets Nos2 expression in the colonic epithelium
por: Eshelman, Melanie A., et al.
Publicado: (2019)

High Intrinsic Oncogenic Potential in the Myc-Box-Deficient Hydra Myc3 Protein
por: Lechable, Marion, et al.
Publicado: (2023)

WNT-mediated gene gating: a novel principle connecting oncogenic super-enhancers with the nuclear pore to drive pathological expression of MYC
por: Göndör, Anita
Publicado: (2020)

Novel oncogene 5MP1 reprograms c-Myc translation initiation to drive malignant phenotypes in colorectal cancer
por: Sato, Kuniaki, et al.
Publicado: (2019)

Oncogene addiction to c-MYC in myeloma cells
por: Holien, Toril, et al.
Publicado: (2012)

Myc, Oncogenic Protein Translation, and the Role of Polyamines
por: Flynn, Andrea T., et al.
Publicado: (2018)

A critical appraisal of the immunohistochemical detection of the c-myc oncogene product in colorectal cancer.
por: Jones, D. J., et al.
Publicado: (1987)

Genetic lesions in MYC and STAT3 drive oncogenic transcription factor overexpression in plasmablastic lymphoma
por: Garcia-Reyero, Julia, et al.
Publicado: (2020)

Detection of the c-myc oncogene product in testicular cancer.
por: Sikora, K., et al.
Publicado: (1985)

Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency
por: Barna, Maria, et al.
Publicado: (2008)

Targeting oncogenic Myc as a strategy for cancer treatment
por: Chen, Hui, et al.
Publicado: (2018)

AMPLIFIED ALLELE OF THE HUMAN N‐myc ONCOGENE IN NEUROBLASTOMAS
por: Yamada, Masao, et al.
Publicado: (1988)

MYC Oncogene Contributions to Release of Cell Cycle Brakes
por: García-Gutiérrez, Lucía, et al.
Publicado: (2019)

Omomyc Reveals New Mechanisms To Inhibit the MYC Oncogene
por: Demma, Mark J., et al.
Publicado: (2019)

ANXA1 (Annexin A1) regulated by MYC (MYC proto-oncogene) promotes the growth of papillary thyroid carcinoma
por: Ying, Xiaomei, et al.
Publicado: (2021)

MYC Immunohistochemistry Predicts MYC Rearrangements by FISH
por: Nwanze, Julum, et al.
Publicado: (2017)

Global role of IGF2BP1 in controlling the expression of Wnt/β-catenin-regulated genes in colorectal cancer cells
por: Singh, Vikash, et al.
Publicado: (2023)

MYC and integrins interplay in colorectal cancer
por: Boudjadi, Salah, et al.
Publicado: (2016)

Detection of the c-myc oncogene product in colonic polyps and carcinomas.
por: Stewart, J., et al.
Publicado: (1986)

Developments in Burkitt’s lymphoma: novel cooperations in oncogenic MYC signaling
por: Spender, Lindsay C, et al.
Publicado: (2014)

Annotating MYC oncogene status with (89)Zr-transferrin imaging
por: Holland, Jason P., et al.
Publicado: (2012)

Regulation of cancer cell metabolism: oncogenic MYC in the driver’s seat
por: Dong, Yang, et al.
Publicado: (2020)

c-myc oncogene product expression and prognosis in operable breast cancer.
por: Locker, A. P., et al.
Publicado: (1989)

Phosphorylation promotes activation-induced cytidine deaminase activity at the Myc oncogene
por: Mu, Yunxiang, et al.
Publicado: (2017)

MYC oncogene is associated with suppression of tumor immunity and targeting Myc induces tumor cell immunogenicity for therapeutic whole cell vaccination
por: Wu, Xiaofang, et al.
Publicado: (2021)

Epigenetic and transcriptional dysregulation of VWA2 associated with a MYC-driven oncogenic program in colorectal cancer
por: González, Beatriz, et al.
Publicado: (2018)

C-myc and N-myc in the developing brain
por: Wey, Alice, et al.
Publicado: (2010)

The Molecular ‘Myc-anisms’ Behind Myc-Driven Tumorigenesis and the Relevant Myc-Directed Therapeutics
por: McAnulty, Jessica, et al.
Publicado: (2020)

MYC sensitises cells to apoptosis by driving energetic demand
por: Edwards-Hicks, Joy, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_cb3asdsavug6tci3k4gakpg527