First-in-class small molecule potentiators of cancer virotherapy

The use of engineered viral strains such as gene therapy vectors and oncolytic viruses (OV) to selectively destroy cancer cells is poised to make a major impact in the clinic and revolutionize cancer therapy. In particular, several studies have shown that OV therapy is safe and well tolerated in hum...

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Detalles Bibliográficos
Autores principales: Dornan, Mark H., Krishnan, Ramya, Macklin, Andrew M., Selman, Mohammed, El Sayes, Nader, Son, Hwan Hee, Davis, Colin, Chen, Andrew, Keillor, Kerkeslin, Le, Penny J., Moi, Christina, Ou, Paula, Pardin, Christophe, Canez, Carlos R., Le Boeuf, Fabrice, Bell, John C., Smith, Jeffrey C., Diallo, Jean-Simon, Boddy, Christopher N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880900/
https://www.ncbi.nlm.nih.gov/pubmed/27226390
http://dx.doi.org/10.1038/srep26786

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