Cargando…
Corepressive function of nuclear receptor coactivator 2 in androgen receptor of prostate cancer cells treated with antiandrogen
BACKGROUND: Recruitment of cofactors in the interaction of the androgen receptor (AR) and AR ligands plays a critical role in determining androgenic/antiandrogenic effects of the AR ligand on signaling, but the functions of key cofactors, including nuclear receptor coactivator (NCOA), remain poorly...
Autores principales: | Takeda, Keisuke, Hara, Noboru, Nishiyama, Tsutomu, Tasaki, Masayuki, Ishizaki, Fumio, Tomita, Yoshihiko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880970/ https://www.ncbi.nlm.nih.gov/pubmed/27225190 http://dx.doi.org/10.1186/s12885-016-2378-y |
Ejemplares similares
-
Dihydrotestosterone synthesis pathways from inactive androgen 5α-androstane-3β,17β-diol in prostate cancer cells: Inhibition of intratumoural 3β-hydroxysteroid dehydrogenase activities by abiraterone
por: Ando, Takashi, et al.
Publicado: (2016) -
“True” Antiandrogens—Selective
Non-Ligand-Binding Pocket Disruptors of Androgen Receptor–Coactivator
Interactions: Novel Tools for Prostate Cancer
por: Caboni, Laura, et al.
Publicado: (2012) -
Androgen deprivation promotes intratumoral synthesis of dihydrotestosterone from androgen metabolites in prostate cancer
por: Ishizaki, Fumio, et al.
Publicado: (2013) -
Antiandrogens Act as Selective Androgen Receptor Modulators at the Proteome Level in Prostate Cancer Cells
por: Brooke, Greg N., et al.
Publicado: (2015) -
Cyclin E as a Coactivator of the Androgen Receptor
por: Yamamoto, Ayako, et al.
Publicado: (2000)