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Nonylphenol Toxicity Evaluation and Discovery of Biomarkers in Rat Urine by a Metabolomics Strategy through HPLC-QTOF-MS

Nonylphenol (NP) was quantified using liquid chromatography tandem mass spectrometry (LC-MS/MS) in the urine and plasma of rats treated with 0, 50, and 250 mg/kg/day of NP for four consecutive days. A urinary metabolomic strategy was originally implemented by high performance liquid chromatography t...

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Detalles Bibliográficos
Autores principales: Zhang, Yan-Xin, Yang, Xin, Zou, Pan, Du, Peng-Fei, Wang, Jing, Jin, Fen, Jin, Mao-Jun, She, Yong-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881126/
https://www.ncbi.nlm.nih.gov/pubmed/27187439
http://dx.doi.org/10.3390/ijerph13050501