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Analgesic effect and possible mechanism of SCH772984 intrathecal injection on rats with bone cancer pain()

This study is to establish a model of rat tibial osteocarcinoma pain, intrathecally inject specific ERK1/2 inhibitors SCH772984, observe the analgesic effect, and discuss the influence of ERK-P90RSK-Fos signal path in bone cancer pain. Forty female SD rats were randomly divided into 5 groups. Establ...

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Detalles Bibliográficos
Autores principales:	Bian, Juhua, Zhu, Shanshan, Ma, Wenwen, Li, Chunwei, Ashraf, Muhammad Aqeel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881153/ https://www.ncbi.nlm.nih.gov/pubmed/27275127 http://dx.doi.org/10.1016/j.jsps.2016.04.017

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