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Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication

The transcription factor Yin Yang 1 (YY1) is frequently overexpressed in cancerous tissues compared to normal tissues and has regulatory roles in cell proliferation, cell viability, epithelial-mesenchymal transition, metastasis and drug/immune resistance. YY1 shares many properties with cancer stem...

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Detalles Bibliográficos
Autores principales: Kaufhold, Samantha, Garbán, Hermes, Bonavida, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881184/
https://www.ncbi.nlm.nih.gov/pubmed/27225481
http://dx.doi.org/10.1186/s13046-016-0359-2