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Pathogen distribution and drug resistance of nephrology patients with urinary tract infections

Objective: Pathogen distribution characteristics of nephrology patients with urinary tract infections are studied, and drug resistance of nephrology and urinary tract infection disease are analyzed, so as to provide sufficient evidence for treatment of patients. Methods: Conduct randomized control s...

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Autores principales: Wang, Yunqian, Li, Huicong, Chen, Baoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881232/
https://www.ncbi.nlm.nih.gov/pubmed/27275125
http://dx.doi.org/10.1016/j.jsps.2016.04.013
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author Wang, Yunqian
Li, Huicong
Chen, Baoping
author_facet Wang, Yunqian
Li, Huicong
Chen, Baoping
author_sort Wang, Yunqian
collection PubMed
description Objective: Pathogen distribution characteristics of nephrology patients with urinary tract infections are studied, and drug resistance of nephrology and urinary tract infection disease are analyzed, so as to provide sufficient evidence for treatment of patients. Methods: Conduct randomized control study of 3500 cases of nephrology patients with urinary tract infections treated in different hospitals from December 2013 to December 2015, isolate pathogens in patients’ urine samples, perform identification and drug sensitive test and then conduct detailed analysis of drug resistance of pathogens. Results: Through isolation of pathogens, it can be found that all pathogens include Escherichia coli, Gram-positive cocci, gram-negative bacteria, fungi, Acinetobacter baumannii, Enterococcus faecalis, and urinary Enterococcus. Among them, proportion of E. coli is the largest. Patients have relatively high drug resistance to ceftriaxone, gentamicin, ciprofloxacin and cotrimoxazole. Conclusion: For nephrology patients with urinary tract infection, the main pathogen is E. coli, which has had some drug resistance. Drug resistance detection of pathogen should be strengthened in clinics, so as to provide strong guidance for clinical treatment and promote effective treatment of patients.
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spelling pubmed-48812322016-06-06 Pathogen distribution and drug resistance of nephrology patients with urinary tract infections Wang, Yunqian Li, Huicong Chen, Baoping Saudi Pharm J Original Article Objective: Pathogen distribution characteristics of nephrology patients with urinary tract infections are studied, and drug resistance of nephrology and urinary tract infection disease are analyzed, so as to provide sufficient evidence for treatment of patients. Methods: Conduct randomized control study of 3500 cases of nephrology patients with urinary tract infections treated in different hospitals from December 2013 to December 2015, isolate pathogens in patients’ urine samples, perform identification and drug sensitive test and then conduct detailed analysis of drug resistance of pathogens. Results: Through isolation of pathogens, it can be found that all pathogens include Escherichia coli, Gram-positive cocci, gram-negative bacteria, fungi, Acinetobacter baumannii, Enterococcus faecalis, and urinary Enterococcus. Among them, proportion of E. coli is the largest. Patients have relatively high drug resistance to ceftriaxone, gentamicin, ciprofloxacin and cotrimoxazole. Conclusion: For nephrology patients with urinary tract infection, the main pathogen is E. coli, which has had some drug resistance. Drug resistance detection of pathogen should be strengthened in clinics, so as to provide strong guidance for clinical treatment and promote effective treatment of patients. Elsevier 2016-05 2016-04-23 /pmc/articles/PMC4881232/ /pubmed/27275125 http://dx.doi.org/10.1016/j.jsps.2016.04.013 Text en © 2016 Production and Hosting by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Wang, Yunqian
Li, Huicong
Chen, Baoping
Pathogen distribution and drug resistance of nephrology patients with urinary tract infections
title Pathogen distribution and drug resistance of nephrology patients with urinary tract infections
title_full Pathogen distribution and drug resistance of nephrology patients with urinary tract infections
title_fullStr Pathogen distribution and drug resistance of nephrology patients with urinary tract infections
title_full_unstemmed Pathogen distribution and drug resistance of nephrology patients with urinary tract infections
title_short Pathogen distribution and drug resistance of nephrology patients with urinary tract infections
title_sort pathogen distribution and drug resistance of nephrology patients with urinary tract infections
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881232/
https://www.ncbi.nlm.nih.gov/pubmed/27275125
http://dx.doi.org/10.1016/j.jsps.2016.04.013
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