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mFOLFOX6 Chemotherapy after Resection of Anal Canal Mucinous Adenocarcinoma

Because of their rarity, there are no clear guidelines for the treatment of anal carcinomas; such tumors are normally subjected to the same modalities as recommended for rectal cancer. We report a patient with anal canal mucinous adenocarcinoma, with metastases in the pararectal and right inguinal l...

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Detalles Bibliográficos
Autores principales: Matsunaga, Mototsugu, Miwa, Keisuke, Oka, Yosuke, Nagasu, Sachiko, Sakaue, Takahiko, Fukahori, Masaru, Ushijima, Tomoyuki, Akagi, Yoshito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881242/
https://www.ncbi.nlm.nih.gov/pubmed/27239184
http://dx.doi.org/10.1159/000446066
Descripción
Sumario:Because of their rarity, there are no clear guidelines for the treatment of anal carcinomas; such tumors are normally subjected to the same modalities as recommended for rectal cancer. We report a patient with anal canal mucinous adenocarcinoma, with metastases in the pararectal and right inguinal lymph nodes, who was treated with abdominoperineal resection followed by mFOLFOX6 chemotherapy for 6 months (12 cycles). The patient has remained recurrence-free thus far, approximately 2 years since the surgery. As the optimal treatments for anal carcinomas have not been fully elucidated, we present this case to highlight a possible course of action for such patients that appears to be effective and promising.