Cargando…

Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology

Primary giant cell tumors of soft tissues (GCT-ST) are extremely rare soft tissue tumors, located in both superficial and deep soft tissues. They resemble osseous giant cell tumors morphologically and immunohistochemically. The tumor exhibits strong positive immunoreactivity for cluster of different...

Descripción completa

Detalles Bibliográficos
Autores principales: Kulkarni, Maithili M, Joshi, Avinash R, Patil, Vinod, Ansari, Tabassum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881402/
https://www.ncbi.nlm.nih.gov/pubmed/27279689
http://dx.doi.org/10.4103/0970-9371.177144
_version_ 1782433952607240192
author Kulkarni, Maithili M
Joshi, Avinash R
Patil, Vinod
Ansari, Tabassum
author_facet Kulkarni, Maithili M
Joshi, Avinash R
Patil, Vinod
Ansari, Tabassum
author_sort Kulkarni, Maithili M
collection PubMed
description Primary giant cell tumors of soft tissues (GCT-ST) are extremely rare soft tissue tumors, located in both superficial and deep soft tissues. They resemble osseous giant cell tumors morphologically and immunohistochemically. The tumor exhibits strong positive immunoreactivity for cluster of differentiation 68 (CD68) within multinucleated osteoclast-like giant cells and focal staining of mononuclear cells. Case reports describing the cytohistological features of this entity are very few. We report a case of GCT-ST of low malignant potential diagnosed on fine needle aspiration (FNA) and confirmed on histological and immunohistochemical studies.
format Online
Article
Text
id pubmed-4881402
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-48814022016-06-08 Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology Kulkarni, Maithili M Joshi, Avinash R Patil, Vinod Ansari, Tabassum J Cytol Case Report Primary giant cell tumors of soft tissues (GCT-ST) are extremely rare soft tissue tumors, located in both superficial and deep soft tissues. They resemble osseous giant cell tumors morphologically and immunohistochemically. The tumor exhibits strong positive immunoreactivity for cluster of differentiation 68 (CD68) within multinucleated osteoclast-like giant cells and focal staining of mononuclear cells. Case reports describing the cytohistological features of this entity are very few. We report a case of GCT-ST of low malignant potential diagnosed on fine needle aspiration (FNA) and confirmed on histological and immunohistochemical studies. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4881402/ /pubmed/27279689 http://dx.doi.org/10.4103/0970-9371.177144 Text en Copyright: © 2016 Journal of Cytology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Kulkarni, Maithili M
Joshi, Avinash R
Patil, Vinod
Ansari, Tabassum
Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology
title Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology
title_full Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology
title_fullStr Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology
title_full_unstemmed Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology
title_short Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology
title_sort giant cell tumor of soft tissues of low malignant potential: a rare diagnosis on fine needle aspiration cytology
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881402/
https://www.ncbi.nlm.nih.gov/pubmed/27279689
http://dx.doi.org/10.4103/0970-9371.177144
work_keys_str_mv AT kulkarnimaithilim giantcelltumorofsofttissuesoflowmalignantpotentialararediagnosisonfineneedleaspirationcytology
AT joshiavinashr giantcelltumorofsofttissuesoflowmalignantpotentialararediagnosisonfineneedleaspirationcytology
AT patilvinod giantcelltumorofsofttissuesoflowmalignantpotentialararediagnosisonfineneedleaspirationcytology
AT ansaritabassum giantcelltumorofsofttissuesoflowmalignantpotentialararediagnosisonfineneedleaspirationcytology