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Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology
Primary giant cell tumors of soft tissues (GCT-ST) are extremely rare soft tissue tumors, located in both superficial and deep soft tissues. They resemble osseous giant cell tumors morphologically and immunohistochemically. The tumor exhibits strong positive immunoreactivity for cluster of different...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881402/ https://www.ncbi.nlm.nih.gov/pubmed/27279689 http://dx.doi.org/10.4103/0970-9371.177144 |
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author | Kulkarni, Maithili M Joshi, Avinash R Patil, Vinod Ansari, Tabassum |
author_facet | Kulkarni, Maithili M Joshi, Avinash R Patil, Vinod Ansari, Tabassum |
author_sort | Kulkarni, Maithili M |
collection | PubMed |
description | Primary giant cell tumors of soft tissues (GCT-ST) are extremely rare soft tissue tumors, located in both superficial and deep soft tissues. They resemble osseous giant cell tumors morphologically and immunohistochemically. The tumor exhibits strong positive immunoreactivity for cluster of differentiation 68 (CD68) within multinucleated osteoclast-like giant cells and focal staining of mononuclear cells. Case reports describing the cytohistological features of this entity are very few. We report a case of GCT-ST of low malignant potential diagnosed on fine needle aspiration (FNA) and confirmed on histological and immunohistochemical studies. |
format | Online Article Text |
id | pubmed-4881402 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-48814022016-06-08 Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology Kulkarni, Maithili M Joshi, Avinash R Patil, Vinod Ansari, Tabassum J Cytol Case Report Primary giant cell tumors of soft tissues (GCT-ST) are extremely rare soft tissue tumors, located in both superficial and deep soft tissues. They resemble osseous giant cell tumors morphologically and immunohistochemically. The tumor exhibits strong positive immunoreactivity for cluster of differentiation 68 (CD68) within multinucleated osteoclast-like giant cells and focal staining of mononuclear cells. Case reports describing the cytohistological features of this entity are very few. We report a case of GCT-ST of low malignant potential diagnosed on fine needle aspiration (FNA) and confirmed on histological and immunohistochemical studies. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4881402/ /pubmed/27279689 http://dx.doi.org/10.4103/0970-9371.177144 Text en Copyright: © 2016 Journal of Cytology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Kulkarni, Maithili M Joshi, Avinash R Patil, Vinod Ansari, Tabassum Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology |
title | Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology |
title_full | Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology |
title_fullStr | Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology |
title_full_unstemmed | Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology |
title_short | Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology |
title_sort | giant cell tumor of soft tissues of low malignant potential: a rare diagnosis on fine needle aspiration cytology |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881402/ https://www.ncbi.nlm.nih.gov/pubmed/27279689 http://dx.doi.org/10.4103/0970-9371.177144 |
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