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Protective Effect of Tyrosol and S-Adenosylmethionine against Ethanol-Induced Oxidative Stress of Hepg2 Cells Involves Sirtuin 1, P53 and Erk1/2 Signaling
Oxidative stress plays a major role in ethanol-induced liver damage, and agents with antioxidant properties are promising as therapeutic opportunities in alcoholic liver disease. In the present work, we investigated the effect of S-adenosylmethionine (AdoMet), Tyrosol (Tyr), and their combination on...
Autores principales: | Stiuso, Paola, Bagarolo, Maria Libera, Ilisso, Concetta Paola, Vanacore, Daniela, Martino, Elisa, Caraglia, Michele, Porcelli, Marina, Cacciapuoti, Giovanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881448/ https://www.ncbi.nlm.nih.gov/pubmed/27128904 http://dx.doi.org/10.3390/ijms17050622 |
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