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Data Interoperability of Whole Exome Sequencing (WES) Based Mutational Burden Estimates from Different Laboratories

Immune checkpoint inhibitors, which unleash a patient’s own T cells to kill tumors, are revolutionizing cancer treatment. Several independent studies suggest that higher non-synonymous mutational burden assessed by whole exome sequencing (WES) in tumors is associated with improved objective response...

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Detalles Bibliográficos
Autores principales:	Qiu, Ping, Pang, Ling, Arreaza, Gladys, Maguire, Maureen, Chang, Ken C. N., Marton, Matthew J., Levitan, Diane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881477/ https://www.ncbi.nlm.nih.gov/pubmed/27136543 http://dx.doi.org/10.3390/ijms17050651

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