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G Protein-Coupled Receptor Signaling in Stem Cells and Cancer

G protein-coupled receptors (GPCRs) are a large superfamily of cell-surface signaling proteins that bind extracellular ligands and transduce signals into cells via heterotrimeric G proteins. GPCRs are highly tractable drug targets. Aberrant expression of GPCRs and G proteins has been observed in var...

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Detalles Bibliográficos
Autores principales: Lynch, Jennifer R., Wang, Jenny Yingzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881529/
https://www.ncbi.nlm.nih.gov/pubmed/27187360
http://dx.doi.org/10.3390/ijms17050707