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The Growing Complexity of Cancer Cell Response to DNA-Damaging Agents: Caspase 3 Mediates Cell Death or Survival?

It is widely stated that wild-type p53 either mediates the activation of cell cycle checkpoints to facilitate DNA repair and promote cell survival, or orchestrates apoptotic cell death following exposure to cancer therapeutic agents. This reigning paradigm has been challenged by numerous discoveries...

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Detalles Bibliográficos
Autores principales:	Mirzayans, Razmik, Andrais, Bonnie, Kumar, Piyush, Murray, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881530/ https://www.ncbi.nlm.nih.gov/pubmed/27187358 http://dx.doi.org/10.3390/ijms17050708

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