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Is the Efficiency of RNA Silencing Evolutionarily Regulated?

Small interfering RNAs (siRNAs) and microRNAs (miRNAs) regulate gene expression in a sequence-specific manner. Genes with partial complementarity to siRNA/miRNA sequences in their 3′-untranslated regions (UTRs) are suppressed by a mechanism referred to as the siRNA off-target effect or miRNA-mediate...

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Detalles Bibliográficos
Autor principal:	Ui-Tei, Kumiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881541/ https://www.ncbi.nlm.nih.gov/pubmed/27187367 http://dx.doi.org/10.3390/ijms17050719

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