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Mechanisms of Cell Killing Response from Low Linear Energy Transfer (LET) Radiation Originating from (177)Lu Radioimmunotherapy Targeting Disseminated Intraperitoneal Tumor Xenografts
Radiolabeled antibodies (mAbs) provide efficient tools for cancer therapy. The combination of low energy β(−)-emissions (500 keV(max); 130 keV(ave)) along with a γ-emission for imaging makes (177)Lu (T(1/2) = 6.7 day) a suitable radionuclide for radioimmunotherapy (RIT) of tumor burdens possibly too...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881558/ https://www.ncbi.nlm.nih.gov/pubmed/27196891 http://dx.doi.org/10.3390/ijms17050736 |