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A Tumor-Specific Neo-Antigen Caused by a Frameshift Mutation in BAP1 Is a Potential Personalized Biomarker in Malignant Peritoneal Mesothelioma
Malignant peritoneal mesothelioma (MPM) is an aggressive rare malignancy associated with asbestos exposure. A better understanding of the molecular pathogenesis of MPM will help develop a targeted therapy strategy. Oncogene targeted depth sequencing was performed on a tumor sample and paired periphe...
Autores principales: | Lai, Jun, Zhou, Zhan, Tang, Xiao-Jing, Gao, Zhi-Bin, Zhou, Jie, Chen, Shu-Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881561/ https://www.ncbi.nlm.nih.gov/pubmed/27187383 http://dx.doi.org/10.3390/ijms17050739 |
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